USMLE Step I Exam - Hematopoietic, Lymphoreticular, Musculoskeletal, Renal, and Urinary Systems

The USMLE Step I Exam, in addition to covering general principles related to various scientific fields, covers a wide range of information regarding the major systems of the body. The exam primarily focuses on the normal operations of each system, the disorders, diseases, and other abnormal conditions that might affect each system, how to treat each system if there is a problem, and what factors might affect the patient's treatment. The topics covered on the exam related to the hematopoietic, lymphoreticular, musculoskeletal, renal, and urinary systems are actually almost identical to the cardiovascular topics covered on the exam except that each of the topics covered relates to its respective body system instead of the cardiovascular system. This means that the questions on the exam related to the hematopoietic, lymphoreticular, musculoskeletal, renal, and urinary systems are based on topics such as embryonic development, fetal maturation, function of organ and organ structure, perinatal changes, and the structure and function of the cells and tissue that make up the organs in each respective system. The questions on the exam for these systems also cover topics related to the infections, immune disorders, and other abnormal conditions that might affect each system, how each system repairs itself and regenerates cells and tissue, how each system changes as an individual ages, and methods for treating diseases and disorders occurring in that system of the body.

The types of hematopoietic and lymphoreticular diseases and disorders covered on the exam include allergic reactions, autoimmune diseases, endothelial disorders, idiopathic disorders, infections of the blood, mechanical injuries, metabolic disorders, neoplastic disorders, regulatory disorders, traumatic disorders, vascular disorders, and other diseases and disorders that specifically affect the hematopoietic system of the lymphoreticular system. The types of musculoskeletal diseases and disorders covered on the exam include degenerative disorders, idiopathic disorders, infectious disorders, inflammatory disorders, immunologic disorders, mechanical injuries, metabolic disorders, neoplastic disorders, regulatory disorders, structural disorders, traumatic disorders, vascular disorders, and other diseases and disorders that specifically affect the musculoskeletal system. The types of renal and urinary diseases and disorders covered on the exam include infectious disorders, inflammatory disorders, immunologic disorders, mechanical disorders, metabolic disorders, neoplastic disorders, traumatic disorders, vascular disorders, and other diseases and disorders that specifically affect the renal and/or urinary system. The diseases, disorders, and topics mentioned here do not necessarily include every topic that will be covered on the exam, but most of the questions regarding these systems will relate specifically to these topics.